15-BiotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester , 97% , 459426-22-3

CAS NO.：459426-22-3

Empirical Formula: C25H40N4O10S

Molecular Weight: 588.67

MDL number: MFCD08458915

PRODUCT Properties

• Density: 1.33±0.1 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: Soluble in DMSO, DMF, DCM
• pka: 13.90±0.40(Predicted)
• form: solid or viscous liquid
• color: White to light yellow
• Appearance: white to off-beige powder
• InChIKey: DTLVBHCSSNJCMJ-JXQFQVJHSA-N
• SMILES: C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@H]1[C@@]2([H])NC(=O)N[C@@]2([H])CS1

Description and Uses

Biotin-PEG₄-NHS is an amine reactive reagent that contains biotin linked via a four-unit PEG spacer to N-hydroxysuccinimide (NHS), which facilitates the coupling of biotin to primary amines. Biotin-PEG₄-NHS has been used in the biotinylation of proteins and antibodies.

Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Safety

• Precautionary statements: P271-P261-P280
• HS Code: 2942000090