5-Bromo-2,4-dichloropyrimidine , 98% , 36082-50-5

CAS NO.：36082-50-5

Empirical Formula: C4HBrCl2N2

Molecular Weight: 227.87

MDL number: MFCD00127818

EINECS: 629-358-1

PRODUCT Properties

• Melting point: 29-30 °C (lit.)
• Boiling point: 128 °C/15 mmHg (lit.)
• Density: 1.781 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.603(lit.)
• Flash point: >230 °F
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Chloroform (Slightly), Ether (Slightly), Ethyl Acetate (Slightly), Toluene (Slightly)
• pka: -4.26±0.29(Predicted)
• form: Liquid or Low Melting Solid
• color: Clear colorless to light yellow
• Specific Gravity: 1.781
• BRN: 124441
• InChI: InChI=1S/C4HBrCl2N2/c5-2-1-8-4(7)9-3(2)6/h1H
• InChIKey: SIKXIUWKPGWBBF-UHFFFAOYSA-N
• SMILES: C1(Cl)=NC=C(Br)C(Cl)=N1
• CAS DataBase Reference: 36082-50-5(CAS DataBase Reference)

Description and Uses

5-Bromo-2,4-dichloropyrimidine may be employed as starting reagent for the synthesis of positive allosteric modulators for GABA_B receptors (drug-like class of compounds) and pyridinepyrimidine analogs.

Safety

• Symbol(GHS): GHS05,GHS06
• Signal word: Danger
• Hazard statements: H301+H311+H331-H314-H317
• Precautionary statements: P260-P280-P301+P310+P330-P301+P330+P331-P303+P361+P353-P305+P351+P338
• Hazard Codes: T,C
• Risk Statements: 23/24/25-34-43
• Safety Statements: 26-27-36/37/39-45
• RIDADR: UN 3263 8/PG 2
• WGK Germany: 3
• Hazard Note: Toxic/Corrosive
• HazardClass: 8
• PackingGroup: III
• HS Code: 29335990
• Limited Quantities: 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)