A1407912
Brivanib (BMS-540215) , ≥98% , 649735-46-6
CAS NO.：649735-46-6
Empirical Formula: C19 H19 F N4 O3
Molecular Weight: 370.38
MDL number: MFCD13194684
| Pack Size | Price | Stock | Quantity |
| 5MG | RMB247.20 | In Stock |
|
| 10MG | RMB481.60 | In Stock |
|
| 50MG | RMB1911.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.42 |
| storage temp. | Store at -20°C |
| solubility | insoluble in H2O; ≥18.5 mg/mL in DMSO; ≥3.39 mg/mL in EtOH with ultrasonic |
| form | Yellow powder. |
| pka | 14.18±0.20(Predicted) |
| color | White to light brown |
| InChI | 1S/C19H19FN4O3/c1-10-6-13-14(23-10)4-5-15(17(13)20)27-19-18-12(3)16(26-8-11(2)25)7-24(18)22-9-21-19/h4-7,9,11,23,25H,8H2,1-3H3/t11-/m1/s1 |
| InChIKey | WCWUXEGQKLTGDX-LLVKDONJSA-N |
| SMILES | Fc1c2c([nH]c(c2)C)ccc1Oc3ncn[n]4c3c(c(c4)OC[C@H](O)C)C |
Description and Uses
Brivanib is an ATP-competitive inhibitor against human VEGFR2 and FGFR with IC50 of 25 nM and 148 nM, respectively.
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Danger |
| Hazard statements | H360-H373-H361 |
| Precautionary statements | P260-P314-P501-P201-P202-P281-P308+P313-P405-P501 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
