Bisacodyl , ≥98% , 603-50-9

Synonym(s):
4,4′-(2-pyridylmethylene)-bisphenol diacetate;Bisacodyl

Update time: 2022-07-08

Melting point:	138°C
Boiling point:	493.21°C (rough estimate)
Density	1.2545 (rough estimate)
refractive index	1.5614 (estimate)
storage temp.	Sealed in dry,2-8°C
solubility	Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent). It dissolves in dilute mineral acids.
pka	4.69±0.10(Predicted)
form	Solid
color	White to Off-White
Water Solubility	Soluble in alcohol (slightly), ether (slightly), chloroform, and acetone. Insoluble in water.
λmax	220nm(MeOH)(lit.)
Merck	14,1242
Stability:	Stable. Incompatible with strong oxidizing agents.
Major Application	forensics and toxicology pharmaceutical (small molecule) veterinary
InChI	1S/C22H19NO4/c1-15(24)26-19-10-6-17(7-11-19)22(21-5-3-4-14-23-21)18-8-12-20(13-9-18)27-16(2)25/h3-14,22H,1-2H3
InChIKey	KHOITXIGCFIULA-UHFFFAOYSA-N
SMILES	CC(=O)Oc1ccc(cc1)C(c2ccc(OC(C)=O)cc2)c3ccccn3
LogP	3.453 (est)
CAS DataBase Reference	603-50-9(CAS DataBase Reference)
NIST Chemistry Reference	Bisacodyl(603-50-9)
EPA Substance Registry System	Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester) (603-50-9)

Stimulant laxative.

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs	Respiratory system
PPE	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes	Xi
Risk Statements	22-36/37/38
Safety Statements	26-36
WGK Germany	3
RTECS	SM8750000
TSCA	TSCA listed
HS Code	2933399090
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3
Hazardous Substances Data	603-50-9(Hazardous Substances Data)
Toxicity	LD50 orally in rats: >3 g/kg (Schmidt)