9-Borabicyclo[3.3.1]nonane , 0.5MinTHF , 280-64-8

Synonym(s):
9-BBN

CAS NO.：280-64-8

Empirical Formula: C8H15B

Molecular Weight: 122.02

MDL number: MFCD00074742

EINECS: 206-000-9

PRODUCT Properties

• Melting point: 140-142 °C
• Boiling point: 68-70 °C
• Density: 0.894 g/mL at 25 °C
• Flash point: 1 °F
• storage temp.: Flammables area
• solubility: Miscible with ether, hexane, benzene, toluene, carbon tetrachloride, chloroform, dimethylsulfide and dichloromethane. Slightly miscible with cyclohexane, dimethoxyethane, diglyme and dioxane.
• form: liquid
• Water Solubility: reacts
• Sensitive: Air & Moisture Sensitive
• BRN: 605509
• Exposure limits: ACGIH: TWA 50 ppm; STEL 100 ppm (Skin); OSHA: TWA 200 ppm(590 mg/m3); NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3)
• InChI: InChI=1S/C8H15B/c1-3-7-5-2-6-8(4-1)9-7/h7-9H,1-6H2
• InChIKey: FEJUGLKDZJDVFY-OCAPTIKFSA-N
• SMILES: C12BC(CCC1)CCC2
• EPA Substance Registry System: 9-Borabicyclo[3.3.1]nonane (280-64-8)

Description and Uses

9-BBN monomer acts as a selective hydroboration reagent in synthetic organic chemistry. It is employed in Suzuki reactions as well as in the preparation of terminal alcohols by the region selective addition of alkenes followed by oxidative cleavage using hydrogen peroxide. It is also used in copper-catalyzed cross-coupling reactions of organoboron compounds with primary alkyl halides and pseudohalides. It acts as a protecting group for alkenes. Further, it is used as a reactant for Hetero-Diels-Alder reaction for the synthesis of spirocyclic alkaloids. In addition to this, it is used in intramolecular insertion of alkenes into palladium-nitrogen bonds.

Safety

• Symbol(GHS): GHS02,GHS07,GHS08,GHS09
• Signal word: Danger
• Hazard statements: H261-H333-H225-H260-H302-H319-H335-H351-H304-H315-H336-H361f-H373-H411
• Precautionary statements: P210-P231+P232-P280-P370+P378-P402+P404-P403+P235-P201-P273-P301+P310-P331-P223-P303+P361+P353-P305+P351+P338-P405-P501a
• target organs: Central nervous system, Respiratory system
• Hazard Codes: F,Xn,Xi,N
• Risk Statements: 14-20/21/22-36/37/38-36/37-19-14/15-11-67-65-62-51/53-48/20-38-40
• Safety Statements: 16-26-36/37/39-45-43-33-62-61-36/37-29-7/8-37/39
• RIDADR: UN 3399 4.3/PG 1
• WGK Germany: 3
• F: 1-10-34
• TSCA: TSCA listed
• HazardClass: 4.1
• PackingGroup: III
• HS Code: 29319090
• Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• Hazard Classifications: Acute Tox. 4 Oral; Carc. 2; Eye Irrit. 2; Flam. Liq. 2; STOT SE 3; Water-react 1
• Excepted Quantities: Not Permitted as Excepted Quantity