Home Categories Chemical Reagents 1-(tert-Butoxycarbonyl)-3-azetidinemethanol
A1430912

1-(tert-Butoxycarbonyl)-3-azetidinemethanol , 95% , 142253-56-3

CAS NO.:142253-56-3

Empirical Formula: C9H17NO3

Molecular Weight: 187.24

MDL number: MFCD06656141

Pack Size Price Stock Quantity
250MG RMB25.60 In Stock
500MG RMB28.00 In Stock
1G RMB31.20 In Stock
5G RMB118.40 In Stock
25G RMB479.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 55 °C
Boiling point: 268-273℃
Density  1.115
Flash point: 117°(243°F)
storage temp.  2-8°C
solubility  Soluble in Dimethyl sulfoxide (DMSO).
pka 14.82±0.10(Predicted)
form  powder to lump
color  White to Almost white
InChI InChI=1S/C9H17NO3/c1-9(2,3)13-8(12)10-4-7(5-10)6-11/h7,11H,4-6H2,1-3H3
InChIKey HXRDRJKAEYHOBB-UHFFFAOYSA-N
SMILES N1(C(OC(C)(C)C)=O)CC(CO)C1

Description and Uses

1-Boc-Azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). This compound is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

It is an intermediate in organic syntheses

Safety

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  23-26-37-60
TSCA  No
HazardClass  IRRITANT
HS Code  29339900

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