Home Categories Pharmaceutical intermediates 5-Bromo-2-methoxypyridine-3-carboxylic acid
A1476612

5-Bromo-2-methoxypyridine-3-carboxylic acid , ≥97% , 54916-66-4

Synonym(s):
5-Bromo-2-methoxynicotinic acid

CAS NO.:54916-66-4

Empirical Formula: C7H6BrNO3

Molecular Weight: 232.03

MDL number: MFCD06656771

Pack Size Price Stock Quantity
1G RMB28.00 In Stock
5G RMB126.40 In Stock
25g RMB541.60 In Stock
100g RMB2040.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 156-158
Boiling point: 324.8±42.0 °C(Predicted)
Density  1.713
storage temp.  Inert atmosphere,Room Temperature
form  solid
pka 2.97±0.10(Predicted)
Appearance White to off-white Solid
InChI InChI=1S/C7H6BrNO3/c1-12-6-5(7(10)11)2-4(8)3-9-6/h2-3H,1H3,(H,10,11)
InChIKey SJLXURQPRRMPIV-UHFFFAOYSA-N
SMILES C1(OC)=NC=C(Br)C=C1C(O)=O
CAS DataBase Reference 54916-66-4(CAS DataBase Reference)

Description and Uses

5-Bromo-2-methoxy-nicotinic acid is used as an intermediate in pharmaceutical synthesis and can be employed to prepare RXFP1 receptor agonists. Its synthetic products can selectively activate the RXFP1 receptor for the treatment of heart failure, with an EC50 value of approximately 6.3nM.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Safety Statements  24/25
WGK Germany  nwg
Hazard Note  Irritant/Keep Cold
HazardClass  IRRITANT
HS Code  29333990

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