Halofuginonehydrobromide , ≥98%(HPLC) , 64924-67-0

Synonym(s):
trans-(±)-7-Bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]-4(3H)-quinazolinone monohydrobromide

CAS NO.：64924-67-0

Empirical Formula: C16H17BrClN3O3.HBr

Molecular Weight: 495.59

MDL number: MFCD00946455

PRODUCT Properties

• Melting point: 247° (dec)
• storage temp.: Store at -20°C
• solubility: Soluble to 100 mM in DMSO.
• form: Solid
• color: White to off-white
• InChI: InChI=1/C16H17BrClN3O3.BrH/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14;/h5-6,8,14-15,19,23H,1-4,7H2;1H/t14-,15+;/s3
• InChIKey: SJUWEPZBTXEUMU-DWKGARMTNA-N
• SMILES: C12C=C(C(Br)=CC=1N=CN(CC(=O)C[C@@H]1NCCC[C@H]1O)C2=O)Cl.Br |&1:14,19,r|

Description and Uses

Halofuginone hydrobromide (Halofuginone) is a specific collagen Type I inhibitor that antagonize or inhibit the development of new blood vessels, hence can prevent intimal hyperplasia at a vascular anastomosis. It is used in the treatment or prevention of coccidiosis in both humans and animals.

Halogenated derivative of Febrifugine. Halofuginone hydrobromide is used as an antiprotozoal (coccidiostat).

Safety

• Symbol(GHS): GHS06,GHS09
• Signal word: Danger
• Hazard statements: H300+H310+H330-H315-H319-H410
• Precautionary statements: P262-P273-P280-P302+P352+P310-P304+P340+P310-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 22
• RIDADR: UN2811 - class 6.1 - PG 1 - EHS - Toxic solids, organic, n.o.s., HI: all
• WGK Germany: 3
• RTECS: VA2397066