β-Nicotinamideadeninedinucleotidephosphate , 90% , 53-59-8

Synonym(s):
β-NADP;Coenzyme II;NADP;TPN;Triphosphopyridine nucleotide

CAS NO.：53-59-8

Empirical Formula: C21H28N7O17P3

Molecular Weight: 743.41

MDL number: MFCD00067537

EINECS: 200-178-1

PRODUCT Properties

• storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• solubility: H₂O: 50 mg/mL, clear, slightly yellow
• form: powder to crystal
• pka: pKa1 3.9; pKa2 6.1(at 25℃)
• color: White to Orange to Green
• Water Solubility: H2O: soluble 50mg/mL, clear, colorless to faintly yellow
• λmax: 260nm(lit.)
• Merck: 14,6348
• InChIKey: XJLXINKUBYWONI-WFYQBQJJNA-N
• EPA Substance Registry System: Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'.fwdarw.5'-ester with 3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, inner salt (53-59-8)

Description and Uses

Triphosphopyridine nucleotide is a coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. Triphosphopyridine nucleotide serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).

β-Nicotinamide adenine dinucleotide phosphate hydrate is suitable for use in:
the measurement of Glucose-6-phosphate dehydrogenase activity
the Cytochrome P450 3A4 assay as a part of NADPH-regenerating system
the Cytochrome P450 2D6 assay as a part of NADPH-regenerating system
the determination of Glucose-6-phosphate content

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: UU3440000
• F: 10-21
• HS Code: 2934.99.9001