Home Categories Biochemical Engineering β-Nicotinamideadeninedinucleotidephosphate
A1568750

β-Nicotinamideadeninedinucleotidephosphate , 90% , 53-59-8

Synonym(s):
β-NADP;Coenzyme II;NADP;TPN;Triphosphopyridine nucleotide

CAS NO.:53-59-8

Empirical Formula: C21H28N7O17P3

Molecular Weight: 743.41

MDL number: MFCD00067537

EINECS: 200-178-1

Pack Size Price Stock Quantity
250mg RMB55.20 In Stock
1g RMB139.20 In Stock
5g RMB486.40 In Stock
25g RMB1702.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

storage temp.  Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility  H2O: 50 mg/mL, clear, slightly yellow
form  powder to crystal
pka pKa1 3.9; pKa2 6.1(at 25℃)
color  White to Orange to Green
Water Solubility  H2O: soluble 50mg/mL, clear, colorless to faintly yellow
λmax 260nm(lit.)
Merck  14,6348
InChIKey XJLXINKUBYWONI-WFYQBQJJNA-N
SMILES O.NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](OP(O)(O)=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O
EPA Substance Registry System Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'.fwdarw.5'-ester with 3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, inner salt (53-59-8)

Description and Uses

Triphosphopyridine nucleotide is a coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. Triphosphopyridine nucleotide serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).

β-Nicotinamide adenine dinucleotide phosphate hydrate is suitable for use in:
the measurement of Glucose-6-phosphate dehydrogenase activity
the Cytochrome P450 3A4 assay as a part of NADPH-regenerating system
the Cytochrome P450 2D6 assay as a part of NADPH-regenerating system
the determination of Glucose-6-phosphate content

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  UU3440000
10-21
TSCA  TSCA listed
HS Code  2934.99.9001
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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