5-(4-Bromophenyl)-4,6-dichloropyrimidine , >98.0%(GC) , 146533-41-7

CAS NO.：146533-41-7

Empirical Formula: C10H5BrCl2N2

Molecular Weight: 303.97

MDL number: MFCD13151897

PRODUCT Properties

• Melting point: 98.0 to 102.0 °C
• Boiling point: 368.7±42.0 °C(Predicted)
• Density: 1.677±0.06 g/cm3(Predicted)
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: Chloroform (Slightly), DMSO (Slightly)
• form: Solid
• pka: -4.92±0.26(Predicted)
• color: Off-White
• Sensitive: Light Sensitive
• InChI: InChI=1S/C10H5BrCl2N2/c11-7-3-1-6(2-4-7)8-9(12)14-5-15-10(8)13/h1-5H
• InChIKey: WEEFLZORZXLIJE-UHFFFAOYSA-N
• SMILES: C1=NC(Cl)=C(C2=CC=C(Br)C=C2)C(Cl)=N1

Description and Uses

5 - (4-Bromophenyl)-4, 6- dichloropyrimidine is a key intermediate and has a wide range of applications in the pharmaceutical and chemical fields.

5-(4-Bromophenyl)-4,6-dichloropyrimidine is a reactant used in the synthesis of Macitentan, an orally active dual endothelin receptor antagonist.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
• HS Code: 2933599590