2-(2-Bromoethyl)-1,3-dioxolane , >90.0%(GC) , 18742-02-4

Synonym(s):
3-Bromopropionaldehyde ethylene acetal

CAS NO.：18742-02-4

Empirical Formula: C5H9BrO2

Molecular Weight: 181.03

MDL number: MFCD00003216

EINECS: 242-551-1

PRODUCT Properties

• Boiling point: 68-70 °C8 mm Hg(lit.)
• Density: 1.542 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.479(lit.)
• Flash point: 149 °F
• storage temp.: 2-8°C
• solubility: Chloroform (Sparingly), Ethyl Acetate (Slightly)
• form: clear liquid
• color: brownish-yellow
• Specific Gravity: 1.541.542
• Water Solubility: immiscible
• Sensitive: Light Sensitive
• BRN: 103516
• InChI: 1S/C5H9BrO2/c6-2-1-5-7-3-4-8-5/h5H,1-4H2
• InChIKey: GGZQLTVZPOGLCC-UHFFFAOYSA-N
• SMILES: BrCCC1OCCO1
• CAS DataBase Reference: 18742-02-4(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Bromoethyl)-1,3-dioxolane(18742-02-4)

Description and Uses

2-(2-Bromoethyl)-1,3-dioxolane is used as a pharmaceutical intermediate, dioxolanes, acetals, ketals, building blocks, chemical synthesis, organic building blocks and oxygen compounds. 1,1-(Ethylenedioxy)-3-bromopropane is used in the synthesis of EGFR inhibitors. Also used in the synthesis of orally active agents of cancer and cell proliferation with quinoline substructures. It is also used as flavouring agent.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301-H315-H319-H335
• Precautionary statements: P301+P310+P330-P302+P352-P305+P351+P338
• target organs: Respiratory system
• PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
• Hazard Codes: Xn,Xi
• Risk Statements: 22-36/37/38
• Safety Statements: 26-37/39
• RIDADR: UN 2810 6.1/PG 3
• WGK Germany: 2
• F: 8-9
• TSCA: TSCA listed
• HazardClass: 6.1
• PackingGroup: Ⅲ
• HS Code: 29329990
• Storage Class: 6.1C - Combustible acute toxic Cat.3; toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Acute Tox. 3 Oral; Eye Irrit. 2; Skin Irrit. 2; STOT SE 3
• Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)