A2170556
Bromo-PEG6-t-butylester , 97% , 1393330-41-0
CAS NO.:1393330-41-0
Empirical Formula: C19 H37 Br O8
Molecular Weight: 473.4
MDL number: MFCD22574809
Pack Size | Price | Stock | Quantity |
50mg | RMB479.20 | In Stock |
|
250mg | RMB1599.20 | In Stock |
|
1g | RMB3999.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Boiling point: | 489.9±40.0 °C(Predicted) |
Density | 1.192±0.06 g/cm3(Predicted) |
storage temp. | Storage temp. 2-8°C |
form | Liquid |
color | Colorless to light yellow |
InChI | InChI=1S/C19H37BrO8/c1-19(2,3)28-18(21)4-6-22-8-10-24-12-14-26-16-17-27-15-13-25-11-9-23-7-5-20/h4-17H2,1-3H3 |
InChIKey | MCRDORXGTMATBG-UHFFFAOYSA-N |
SMILES | C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCBr |
Description and Uses
Bromo-PEG6-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Bromo-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Safety
Symbol(GHS) | ![]() GHS07 |
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501 |