Cimetidine , 99% , 51481-61-9

Synonym(s):
SKF-92334

CAS NO.：51481-61-9

Empirical Formula: C10H16N6S

Molecular Weight: 252.34

MDL number: MFCD00133296

EINECS: 257-232-2

PRODUCT Properties

• Melting point: 139-144°C
• Boiling point: 476.2±55.0 °C(Predicted)
• Density: 1.2583 (rough estimate)
• refractive index: 1.5700 (estimate)
• storage temp.: 2-8°C
• solubility: Slightly soluble in water, soluble in ethanol (96 per cent), practically insoluble in methylene chloride. It dissolves in dilute mineral acids.
• form: Solid
• pka: pKa 6.80 (Uncertain)
• color: White to Off-White
• Water Solubility: 0.5 g/100 mL at 20 ºC
• Merck: 14,2279
• InChIKey: AQIXAKUUQRKLND-UHFFFAOYSA-N
• CAS DataBase Reference: 51481-61-9(CAS DataBase Reference)
• NIST Chemistry Reference: Cimetidine(51481-61-9)
• IARC: 3 (Vol. 50) 1990
• EPA Substance Registry System: Guanidine, N-cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]- (51481-61-9)

Description and Uses

Cimetidine is a representative of first-generation antihistamine drugs that block H2 receptors.

antibacterial

Safety

• Symbol(GHS): GHS08
• Signal word: Danger
• Hazard statements: H303-H360
• Precautionary statements: P202-P405-P501a-P201-P280-P308+P313
• Hazard Codes: T,Xn
• Risk Statements: 60-42/43-36/37/38-20/22
• Safety Statements: 53-26-36/37/39-45-36-22
• WGK Germany: 3
• RTECS: MF0035500
• HS Code: 29339900
• Hazardous Substances Data: 51481-61-9(Hazardous Substances Data)
• Toxicity: LD50 in mice, rats (mg/kg): 2600, 5000 orally; 150, 106 i.v.; 470, 650 i.p. (Brimblecombe)