A2288012
o-Chloronitrobenzene , standardforGC,>99.5%(GC) , 88-73-3
CAS NO.：88-73-3
Empirical Formula: C6H4ClNO2
Molecular Weight: 157.55
MDL number: MFCD00007061
EINECS: 201-854-9
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 31-33 °C (lit.) |
| Boiling point: | 246 °C (lit.) |
| Density | 1.348 g/mL at 25 °C (lit.) |
| vapor density | 5.4 (vs air) |
| vapor pressure | 0.04 mm Hg ( 25 °C) |
| refractive index | 1.5520 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | alcohol: soluble |
| form | Fused Crystalline Mass |
| color | Yellow |
| PH | 6 (0.4g/l, H2O, 20℃) |
| explosive limit | 1.15-13.1%(V) |
| Water Solubility | 0.43 g/L (20 ºC) |
| Merck | 14,2151 |
| BRN | 509273 |
| Henry's Law Constant | 1.1×100 mol/(m3Pa) at 25℃, Altschuh et al. (1999) |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents, strong bases, alkali metals. |
| InChI | 1S/C6H4ClNO2/c7-5-3-1-2-4-6(5)8(9)10/h1-4H |
| InChIKey | BFCFYVKQTRLZHA-UHFFFAOYSA-N |
| SMILES | [O-][N+](=O)c1ccccc1Cl |
| CAS DataBase Reference | 88-73-3(CAS DataBase Reference) |
| IARC | 2B (Vol. 65, 123) 2020 |
| NIST Chemistry Reference | Benzene, 1-chloro-2-nitro-(88-73-3) |
| EPA Substance Registry System | o-Chloronitrobenzene (88-73-3) |
Description and Uses
1-Chloro-2-nitrobenzene was used in the synthesis of 1-hydroxybenzotriazole derivatives. It is important as a precursor to other compounds due to the two reactive sites present on the molecule.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301+H311 |
| Precautionary statements | P264-P270-P280-P301+P310-P302+P352+P312-P361+P364 |
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Statements | 22-24-52-53-52/53 |
| Safety Statements | 36/37/39-45-60-38-28A |
| RIDADR | UN 1578 6.1/PG 2 |
| WGK Germany | 2 |
| RTECS | CZ0875000 |
| Autoignition Temperature | 500 °F |
| Hazard Note | Toxic |
| TSCA | TSCA listed |
| HazardClass | 6.1 |
| PackingGroup | II |
| HS Code | 29049085 |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| Hazard Classifications | Acute Tox. 3 Dermal Acute Tox. 3 Oral |
| Hazardous Substances Data | 88-73-3(Hazardous Substances Data) |
| REACH Registrations | Active |
| Limited Quantities | 100ml (liquid) or 0.5 Kg (solid) |
| Excepted Quantities | Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml) |
