N-(Carbobenzyloxy)-L-phenylalanine , 98% , 1161-13-3

Synonym(s):
N-(Carbobenzyloxy)-L-phenylalanine;Z-L-Phenylalanine

CAS NO.：1161-13-3

Empirical Formula: C17H17NO4

Molecular Weight: 299.32

MDL number: MFCD00020418

EINECS: 214-599-3

PRODUCT Properties

• Melting point: 85-87 °C(lit.)
• Boiling point: 440.65°C (rough estimate)
• alpha: 5 º (c=5,acetic acid)
• Density: 1.1441 (rough estimate)
• refractive index: 5.3 ° (C=4, AcOH)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: DMF (Sparingly), DMSO (Slightly), Methanol (Slightly)
• pka: 3.86±0.10(Predicted)
• form: Powder
• color: White to off-white
• optical activity: [α]20/D +5°, c = 5 in acetic acid
• BRN: 2222826
• Major Application: peptide synthesis
• InChI: 1S/C17H17NO4/c19-16(20)15(11-13-7-3-1-4-8-13)18-17(21)22-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2,(H,18,21)(H,19,20)/t15-/m0/s1
• InChIKey: RRONHWAVOYADJL-HNNXBMFYSA-N
• SMILES: OC(=O)[C@H](Cc1ccccc1)NC(=O)OCc2ccccc2
• CAS DataBase Reference: 1161-13-3(CAS DataBase Reference)

Description and Uses

N-Cbz-L-Phenylalanine is used in the synthesis of neurokinin antagonists. Furthermore it is used in the preparation of Co(II), Zn(II), and Cd(II) complexes with N-benzyloxycarbonyl-S-phen ylalanine that displays antimicrobial activity against common strains of bacteria.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P271-P280
• PPE: Eyeshields, Gloves, type N95 (US)
• Hazard Codes: Xn
• Risk Statements: 62-36/37/38-20/21/22
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• RTECS: AY4343000
• HS Code: 29242990
• Storage Class: 11 - Combustible Solids