Carbadox , Analysis standard , 6804-07-5

Synonym(s):
3-(2-Quinoxalinylmethylene)carbazic acid methyl ester N,N′-dioxide

CAS NO.：6804-07-5

Empirical Formula: C11H10N4O4

Molecular Weight: 262.22

MDL number: MFCD00057293

EINECS: 229-879-0

PRODUCT Properties

• Melting point: 239-240°C
• Boiling point: 405.47°C (rough estimate)
• Density: 1.3602 (rough estimate)
• refractive index: 1.6000 (estimate)
• Flash point: 18°(64°F)
• storage temp.: 2-8°C
• solubility: DMSO (Slightly, Sonicated)
• form: powder
• pka: 10.51±0.46(Predicted)
• color: Yellow to Dark Yellow
• Water Solubility: Soluble in 1N NaOH (50 mg/ml), and water (partly).
• Stability: Light Sensitive
• InChI: 1S/C11H10N4O4/c1-19-11(16)13-12-6-8-7-14(17)9-4-2-3-5-10(9)15(8)18/h2-7H,1H3,(H,13,16)/b12-6+
• InChIKey: OVGGLBAWFMIPPY-WUXMJOGZSA-N
• SMILES: COC(=O)N\N=C\c1cn(=O)c2ccccc2n1=O
• CAS DataBase Reference: 6804-07-5
• EPA Substance Registry System: Hydrazinecarboxylic acid, 2-[(1,4-dioxido-2-quinoxalinyl)methylene]-, methyl ester (6804-07-5)

Description and Uses

Carbadox has been used to suppress aldosterone production, to study the spread of shiga toxin-producing Escherichia coli (STEC) strains, and to compare different antimicrobial activities. Carbadox is a quinoxaline-di-N-oxide antibiotic that is generally used in feed to swine to prevent dysentery and improve feed efficiency. It inhibits bacteria by intercalation and induction of mutations in bacterial genome.

Safety

• Symbol(GHS): GHS02,GHS07,GHS08
• Signal word: Danger
• Hazard statements: H228-H302-H350
• Precautionary statements: P201-P210-P240-P280-P405-P501a
• Hazard Codes: F,T
• Risk Statements: 45-11-22
• Safety Statements: 53-45
• RIDADR: UN 1325 4.1/PG 2
• WGK Germany: 3
• RTECS: FE2779000
• HazardClass: 4.1
• HS Code: 29339900
• Storage Class: 4.1B - Flammable solid hazardous materials
• Hazard Classifications: Acute Tox. 4 Oral; Carc. 1B; Flam. Sol. 1
• Hazardous Substances Data: 6804-07-5(Hazardous Substances Data)