18-Crown-6 , Used for chromatography, ≥99.0%(GC) , 17455-13-9
Synonym(s):
1,4,7,10,13,16-Hexaoxacyclooctadecane;1,4,7,10,13,16-Hexaoxacyclooctadecane, 18-Crown-6;18C6;Crown ether/18-Crown-6
CAS NO.：17455-13-9
Empirical Formula: C12H24O6
Molecular Weight: 264.32
MDL number: MFCD00005113
EINECS: 241-473-5
| Pack Size | Price | Stock | Quantity |
| 5G | RMB407.20 | In Stock |
|
| 25G | RMB1623.20 | In Stock |
|
| 100g | RMB4479.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 42-45 °C(lit.) |
| Boiling point: | 116°C 0,2mm |
| Density | 1,175 g/cm3 |
| refractive index | 1.4580 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Slightly), Methanol (Very Slightly) |
| form | Crystals or Crystalline Mass or Liquid |
| color | White or clear colorless |
| Water Solubility | SOLUBLE |
| Sensitive | Hygroscopic |
| Merck | 14,2602 |
| BRN | 1619616 |
| Stability: | Stable. Incompatible with strong acids, strong oxidizing agents. |
| InChIKey | XEZNGIUYQVAUSS-UHFFFAOYSA-N |
| CAS DataBase Reference | 17455-13-9(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,4,7,10,13,16-Hexaoxacyclooctadecane(17455-13-9) |
| EPA Substance Registry System | 1,4,7,10,13,16-Hexaoxacyclooctadecane (17455-13-9) |
Description and Uses
18-Crown-6 is used as an efficient phase transfer catalyst and as a complexing agent with a variety of small cation. It is involved in the synthesis of diaryl ethers, diaryl thioethers, and diarylamines mediated by potassium fluoride-alumina and 18-crown-6. It facilitates the solubility of potassium permanganate in benzene, which is used for oxidizing the organic compounds. It is used to accelerate various substitution reactions as well as enhances the power of nucleophiles such as potassium acetate. It is utilized in the alkylation reactions in the presence of potassium carbonate, N-alkylation of glutarimide and succinimide with dimethylcarbonate. The complex formed by its reaction with potassium cyanide acts as a catalyst in the cyanosilylation of aldehydes, ketones and quinines with trimethylsilyl cyanide (TMSCN).
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P501 |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/37/38-36-20/22-20/21/22 |
| Safety Statements | 26-36-39 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| RTECS | MP4500000 |
| F | 10 |
| TSCA | Yes |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29329995 |
| Toxicity | LD50 orally in Rabbit: 525 mg/kg LD50 dermal Rabbit 3888 mg/kg |
