A2462012
CYT387 , ≥98% , 1056634-68-4
CAS NO.：1056634-68-4
Empirical Formula: C23H22N6O2
Molecular Weight: 414.46
MDL number: MFCD16038899
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB257.60 | In Stock |
|
| 10MG | RMB455.20 | In Stock |
|
| 50MG | RMB1519.20 | In Stock |
|
| 100MG | RMB2948.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.292 |
| storage temp. | Store at -20°C |
| solubility | insoluble in EtOH; insoluble in H2O; ≥20.7 mg/mL in DMSO |
| pka | 10.94±0.46(Predicted) |
| form | Orange powder. |
| color | Light yellow to yellow |
| InChI | InChI=1S/C23H22N6O2/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)27-19-5-7-20(8-6-19)29-13-15-31-16-14-29/h1-9,11H,12-16H2,(H,25,30)(H,26,27,28) |
| InChIKey | ZVHNDZWQTBEVRY-UHFFFAOYSA-N |
| SMILES | C(NCC#N)(=O)C1=CC=C(C2C=CN=C(NC3=CC=C(N4CCOCC4)C=C3)N=2)C=C1 |
| CAS DataBase Reference | 1056634-68-4 |
Description and Uses
CYT387 inhibits Janus kinase 1 (JAK1) and Janus kinase (JAK2). These kinases are part of the JAK-STAT pathway and dysregulated functions are involved with hematology, oncology and inflammatory diseases.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
