A2475412
CHIR-98014 , 98% , 252935-94-7
Synonym(s):
GSK-3 Inhibitor XXIX, CHIR98014 - CAS 252935-94-7 - Calbiochem
CAS NO.：252935-94-7
Empirical Formula: C20H17Cl2N9O2
Molecular Weight: 486.31
MDL number: MFCD10565922
| Pack Size | Price | Stock | Quantity |
| 5MG | RMB576.80 | In Stock |
|
| 10mg | RMB1007.20 | In Stock |
|
| 25MG | RMB2015.20 | In Stock |
|
| 50mg | RMB3383.20 | In Stock |
|
| 100mg | RMB5279.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.62 |
| storage temp. | -20°C |
| solubility | insoluble in H2O; insoluble in EtOH; ≥8.1 mg/mL in DMSO with gentle warming |
| form | powder |
| color | white to brown |
| InChIKey | MDZCSIDIPDZWKL-UHFFFAOYSA-N |
| SMILES | NC1=C(C=CC(NCCNC2=NC(C3=C(Cl)C=C(Cl)C=C3)=C(N4C=CN=C4)C=N2)=N1)[N+]([O-])=O |
Description and Uses
CHIR 98014 has been used for the generation of small molecules neural progenitor cells and differentiation towards motor neurons. It has also been used as a Wnt/β-catenin pharmacological agonist in the cell-conditioned medium to perform chromatin immunoprecipitation (ChIP) studies in HT22 neurons.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301-H310+H330 |
| Precautionary statements | P260-P262-P264-P270-P271-P280-P284-P301+P310-P330-P302+P352-P304+P340-P320-P361+P364-P403+P233-P405-P501 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
