Cefdinir , ≥97%(HPLC) , 91832-40-5

Synonym(s):
[6R-[6α-7beta(Z)]]-7-[[(2-Amino-4-thiazolyl)(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;syn-7-[2-(2-amino-4-thiazolyl)-2-hydroxyiminoacetamido]-3-vinyl-3-cephem-4-carboxylic acid;BMY-28488;FK-482

CAS NO.：91832-40-5

Empirical Formula: C14H13N5O5S2

Molecular Weight: 395.41

MDL number: MFCD00865030

EINECS: 643-088-1

PRODUCT Properties

• Melting point: >180°C dec.
• Density: 1.89±0.1 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,2-8°C
• solubility: dilute HCl: slightly soluble
• pka: 9.70(at 25℃)
• form: solid
• color: Pale Yellow to Light Yellow
• Water Solubility: Soluble in water
• λmax: 295nm(DMSO)(lit.)
• Merck: 14,1920
• BCS Class: 4
• InChIKey: RTXOFQZKPXMALH-GHXIOONMSA-N
• SMILES: N12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N\O)=O)C1=O)SCC(C=C)=C2C(O)=O
• CAS DataBase Reference: 91832-40-5(CAS DataBase Reference)

Description and Uses

Cefdinir is a cephalosporin antibiotic. It is active against numerous Gram-positive and Gram-negative bacteria, including β-lactamase-producing E. coli, K. oxytoca, K. pneumoniae, and P. aeruginosa clinical isolates (MICs = 0.25-16 μg/ml). Cefdinir is protective against sepsis induced by strains of S. aureus or H. influenzae in mice with 50% protective dose (PD₅₀) values of 2.7-35 and 3.1-5.8 mg/kg, respectively. Formulations containing cefdinir have been used in the treatment of Gram-positive and Gram-negative infections.

A broad spectrum antibiotic targeting both Gram-positive and Gram-negative pathogens

Safety

• Symbol(GHS): GHS08
• Signal word: Danger
• Hazard statements: H317-H334
• Precautionary statements: P261-P272-P280-P284-P302+P352+P333+P313+P363-P304+P340+P342+P311-P501
• WGK Germany: 3
• RTECS: XI0367250
• HS Code: 2941906000
• Toxicity: LD50 orl-rat: >5600 mg/kg IYKEDH 23,93,1992