1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine Hydrochloride , 97% , 52605-52-4

Synonym(s):
1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine monohydrochloride;Nefazodone Related Compound A;Trazodone Impurity F (Ph. Eur.)

CAS NO.：52605-52-4

Empirical Formula: C13H19Cl3N2

Molecular Weight: 309.66

MDL number: MFCD00067039

EINECS: 258-038-0

PRODUCT Properties

• Melting point: 198-203 °C(lit.)
• Boiling point: 147℃[at 101 325 Pa]
• vapor pressure: 0Pa at 25℃
• storage temp.: 2-8°C
• solubility: DMSO (Slightly, Heated), Methanol (Slightly, Heated)
• form: powder to crystal
• color: White to Light yellow
• Water Solubility: 3.9g/L at 28℃
• InChI: InChI=1S/C13H18Cl2N2.ClH/c14-5-2-6-16-7-9-17(10-8-16)13-4-1-3-12(15)11-13;/h1,3-4,11H,2,5-10H2;1H
• InChIKey: JVLRNANYLVRULL-UHFFFAOYSA-N
• SMILES: ClC1=CC=CC(N2CCN(CCCCl)CC2)=C1.Cl
• LogP: 0.301 at 28℃
• CAS DataBase Reference: 52605-52-4(CAS DataBase Reference)

Description and Uses

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride is an arylpiperazine compound which is an important intermediate in the preparation of various pharmaceuticals, such as Trazodone (T718500), used to treat depression and post-traumatic stress.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P305+P351+P338
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-20/21/22
• Safety Statements: 26-37/39-24/25
• WGK Germany: 3
• F: 10-21
• HS Code: 2933599550