2-Chloro-6-methylaniline , ≥98.0%(GC) , 87-63-8
Synonym(s):
2-Amino-3-chlorotoluene;6-Chloro-o-toluidine
CAS NO.：87-63-8
Empirical Formula: C7H8ClN
Molecular Weight: 141.6
MDL number: MFCD00007679
EINECS: 201-759-2
| Pack Size | Price | Stock | Quantity |
| 1G | RMB31.20 | In Stock |
|
| 5G | RMB36.80 | In Stock |
|
| 25G | RMB141.60 | In Stock |
|
| 100g | RMB424.00 | In Stock |
|
| 500G | RMB1988.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 10-12 °C(lit.) |
| Boiling point: | 215 °C(lit.) |
| Density | 1.152 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 210 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Oil |
| pka | 2.51±0.10(Predicted) |
| color | Clear Colourless to Pale Purple |
| Water Solubility | Immiscible |
| BRN | 774624 |
| InChIKey | WFNLHDJJZSJARK-UHFFFAOYSA-N |
| CAS DataBase Reference | 87-63-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzenamine, 2-chloro-6-methyl-(87-63-8) |
| EPA Substance Registry System | 6-Chloro-2-methylaniline (87-63-8) |
Description and Uses
2-chloro-6-methylaniline is an important organic synthesis intermediate widely applied to chemical pharmacy, pesticides, and organic synthesis. In the aspects of chemical pharmacy and pesticides, 2-chloro-6-methylaniline can be used as a reaction starting material to participate in the preparation processes of tyrosine kinase inhibitors dasatinib, indazole derivatives with anti-breast cancer activity, 2-methyl-6-chlorophenyl sulfonylurea derivatives with bacteriostatic activity and the like; in the aspect of organic synthesis, 2-chloro-6-methylaniline can introduce chemical groups such as hydrazine, nitro, cyano, halogen (F, Cl, Br), and the like into an aromatic ring through diazotization reaction, thereby participating in wide chemical reactions.
2-Chloro-6-methylaniline is a substituted aniline used in the preparation of various pharmaceutical compounds. 2-Chloro-6-methylaniline showed inhibition of the polymerization of vinyl acetate.
Safety
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H301+H311+H331-H341-H373-H410 |
| Precautionary statements | P201-P273-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-20/21/22 |
| Safety Statements | 26-36-36/37/39 |
| RIDADR | UN 3429 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | XU5100000 |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29214300 |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
