1-Carbobenzoxypiperazine , >95.0%(GC) , 31166-44-6

Synonym(s):
1-(Benzyloxycarbonyl)piperazine;1-Cbz-Piperazine;Benzyl piperazine-1-carboxylate

CAS NO.：31166-44-6

Empirical Formula: C12H16N2O2

Molecular Weight: 220.27

MDL number: MFCD00274317

EINECS: 629-513-3

PRODUCT Properties

• Boiling point: 158-161 °C1.4 mm Hg(lit.)
• Density: 1.142 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.546(lit.)
• Flash point: >230 °F
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: Chloroform (Sparingly), Methanol (Sparingly)
• pka: 8.44±0.10(Predicted)
• form: Oil
• color: Clear Colourless to Pale Yellow
• BRN: 179500
• InChI: InChI=1S/C12H16N2O2/c15-12(14-8-6-13-7-9-14)16-10-11-4-2-1-3-5-11/h1-5,13H,6-10H2
• InChIKey: CTOUWUYDDUSBQE-UHFFFAOYSA-N
• SMILES: N1(C(OCC2=CC=CC=C2)=O)CCNCC1
• CAS DataBase Reference: 31166-44-6(CAS DataBase Reference)

Description and Uses

1-Cbz-piperazine is used in the synthesis of serotonin 5-HT6 and dopamine D2 receptor ligands (1,2). It can also be used for the synthesis of a 11-C labelled ligands for imaging vesicular acetylcholine transporter.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10-23
• HS Code: 29335990