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A2744556

Bis-PEG2-acid , 95% , 19364-66-0

CAS NO.:19364-66-0

Empirical Formula: C8H14O6

Molecular Weight: 206.19

MDL number: MFCD22056315

Pack Size Price Stock Quantity
250mg RMB496.00 In Stock
1g RMB1080.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 66 °C
Boiling point: 407.1±35.0 °C(Predicted)
Density  1.0869 g/cm3(Temp: 4 °C)
storage temp.  Storage temp. 2-8°C
solubility  Soluble in Water, DMF, DMSO
form  Solid
pka 3.97±0.10(Predicted)
color  White to off-white

Description and Uses

Bis-PEG2-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Bis-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501

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