A2744556
Bis-PEG2-acid , 95% , 19364-66-0
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB496.00 | In Stock |
|
| 1g | RMB1080.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 66 °C |
| Boiling point: | 407.1±35.0 °C(Predicted) |
| Density | 1.0869 g/cm3(Temp: 4 °C) |
| storage temp. | Storage temp. 2-8°C |
| solubility | Soluble in Water, DMF, DMSO |
| pka | 3.97±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| InChI | 1S/C8H14O6/c9-7(10)1-3-13-5-6-14-4-2-8(11)12/h1-6H2,(H,9,10)(H,11,12) |
| InChIKey | BOXWYBCUJGWEOJ-UHFFFAOYSA-N |
| SMILES | OC(CCOCCOCCC(O)=O)=O |
Description and Uses
Bis-PEG2-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Bis-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
