2,6-Dichloropyridine , 97% , 2402-78-0

CAS NO.：2402-78-0

Empirical Formula: C5H3Cl2N

Molecular Weight: 147.99

MDL number: MFCD00006244

EINECS: 219-282-3

PRODUCT Properties

• Melting point: 83-86 °C (lit.)
• Boiling point: 211 °C
• Density: 1.5159 (rough estimate)
• refractive index: 1.5500 (estimate)
• Flash point: 110°C
• storage temp.: Inert atmosphere,2-8°C
• solubility: methanol: 50 mg/mL, clear
• pka: -3.02±0.10(Predicted)
• form: Crystalline Powder
• color: White to pink or grayish-white
• PH: 6-7 (H2O, 20℃)(saturated solution)
• Water Solubility: <1 g/L (20 ºC)
• BRN: 108664
• InChI: 1S/C5H3Cl2N/c6-4-2-1-3-5(7)8-4/h1-3H
• InChIKey: FILKGCRCWDMBKA-UHFFFAOYSA-N
• SMILES: Clc1cccc(Cl)n1
• CAS DataBase Reference: 2402-78-0(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2,6-dichloro-(2402-78-0)
• EPA Substance Registry System: 2,6-Dichloropyridine (2402-78-0)

Description and Uses

2,6-Dichloropyridine is an important intermediate that is widely used in the medicine and pesticide research field. It could be used as a starting material to synthesize the pirozadil (Pirozadil) which can be used for reducing blood-fat, and antiplatelet condensation. 2,6-dichloropyridine also can be used to synthetic musk pyridine with alternative natural musk. 2,3,5, 6-TCP produced by further chlorination of 2, 6-dichloropyridine is an important raw material for chlorpyrifos, which is widely used in the world with high efficiency, broad spectrum, and low residue.

2,6-Dichloropyridine is used in the preparation of triazolo and imidazo potassium channel antagonists as antiarrythmic agents.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301-H315-H319
• Precautionary statements: P301+P310+P330-P302+P352-P305+P351+P338
• PPE: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• Hazard Codes: T,Xn
• Risk Statements: 25-36/37/38-22-23/24/25
• Safety Statements: 36/37/39-45-37/39-26-36
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• RTECS: US8400000
• Hazard Note: Toxic
• TSCA: TSCA listed
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29333999
• Storage Class: 6.1C - Combustible acute toxic Cat.3; toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Acute Tox. 3 Oral; Eye Irrit. 2; Skin Irrit. 2
• Toxicity: mouse,LD50,intraperitoneal,115mg/kg (115mg/kg),BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)LIVER: FATTY LIVER DEGERATIONBEHAVIORAL: ANTIPSYCHOTIC,Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967.
• Limited Quantities: 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)