2,5-Dimethylpyrazine , 98% , 123-32-0

CAS NO.：123-32-0

Empirical Formula: C6H8N2

Molecular Weight: 108.14

MDL number: MFCD00006147

EINECS: 204-618-3

PRODUCT Properties

• Melting point: 15°C
• Boiling point: 155 °C (lit.)
• Density: 0.99 g/mL at 25 °C (lit.)
• FEMA: 3272 | 2,5-DIMETHYLPYRAZINE
• refractive index: n20/D 1.502(lit.)
• Flash point: 147 °F
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• form: Liquid
• pka: 2.21±0.10(Predicted)
• Specific Gravity: 0.990
• color: Clear colorless to pale yellow
• PH: 7 (H2O)
• Odor: at 0.10 % in dipropylene glycol. nutty roasted baked potato
• Odor Type: chocolate
• biological source: synthetic
• Sensitive: Hygroscopic
• JECFA Number: 766
• BRN: 107052
• Dielectric constant: 2.4399999999999999
• LogP: 0.64
• CAS DataBase Reference: 123-32-0(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazine, 2,5-dimethyl-(123-32-0)
• EPA Substance Registry System: Pyrazine, 2,5-dimethyl- (123-32-0)

Description and Uses

2,5-Dimethylpyrazine is used as a reagent in the synthesis of bone-targeted proteasome inhibitors for multiple myeloma (MM). 2,5-Dimethylpyrazine is also used in the preparation of 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340); a degredation product of Clavulanic Acid (C563750) which is a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P301+P312+P330
• Hazard Codes: Xn,Xi
• Risk Statements: 22-36/37/38-R22
• Safety Statements: 26-36
• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• RTECS: UQ2800000
• Hazard Note: Irritant
• TSCA: Yes
• HS Code: 29339990