Dibenzyl N,N-Diisopropylphosphoramidite , 98% , 108549-23-1

CAS NO.：108549-23-1

Empirical Formula: C20H28NO2P

Molecular Weight: 345.42

MDL number: MFCD00191988

EINECS: 629-628-9

PRODUCT Properties

• Boiling point: 130 °C0.55 mm Hg(lit.)
• Density: 1.028 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.535(lit.)
• Flash point: 158 °F
• storage temp.: 2-8°C
• solubility: Soluble in chloroform.
• form: Oil
• pka: 4.50±0.70(Predicted)
• color: Clear Colourless
• Water Solubility: THF: soluble(lit.); acetonitrile: soluble(lit.); cold water: insoluble(lit.); dichloromethane: soluble(lit.)
• Sensitive: Moisture Sensitive
• BRN: 3616864
• InChI: InChI=1S/C20H28NO2P/c1-17(2)21(18(3)4)24(22-15-19-11-7-5-8-12-19)23-16-20-13-9-6-10-14-20/h5-14,17-18H,15-16H2,1-4H3
• InChIKey: ANPWLBTUUNFQIO-UHFFFAOYSA-N
• SMILES: P(N(C(C)C)C(C)C)(OCC1=CC=CC=C1)OCC1=CC=CC=C1
• CAS DataBase Reference: 108549-23-1(CAS DataBase Reference)

Description and Uses

Dibenzyl diisopropylphosphoramidite is a versatile phosphitylating agent.

Dibenzyl N,N-diisopropylphosphoramidite may be used for the preparation of phosphopeptides. It is used for the synthesis of a GDP (guanosine diphosphate) analog, SML-8-73-1. It is useful for nucleotide coupling.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H227-H315-H319-H335
• Precautionary statements: P210e-P261-P280a-P305+P351+P338-P405-P501a-P210-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• F: 3-10-21
• HS Code: 29319090