PRODUCT Properties
| Melting point: | -14℃ |
| Boiling point: | 142-144 °C(lit.) |
| Density | 0.99 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 88 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | 50.9g/l |
| pka | -1.35±0.28(Predicted) |
| form | clear liquid |
| Specific Gravity | 0.99 |
| color | Colorless to Light yellow to Light orange |
| PH | 4.5 (10g/l, H2O, 20℃) |
| Water Solubility | insoluble |
| BRN | 106324 |
| InChIKey | FICAQKBMCKEFDI-UHFFFAOYSA-N |
| LogP | 1.431 (est) |
| CAS DataBase Reference | 300-87-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Isoxazole, 3,5-dimethyl-(300-87-8) |
| EPA Substance Registry System | Isoxazole, 3,5-dimethyl- (300-87-8) |
Description and Uses
The optimization of 3,5-dimethylisoxazole derivatives to develop potent inhibitors of the BET (bromodomain and extra terminal domain) bromodomain family with good ligand efficiency. It has hypoglycemic activity.
Safety
| Symbol(GHS) |  GHS02 |
| Signal word | Warning |
| Hazard statements | H226 |
| Precautionary statements | P210-P233-P240-P241+P242+P243-P280-P303+P361+P353-P370+P378-P403+P235-P501-P241-P280a-P501a |
| Hazard Codes | Xn |
| Risk Statements | 10-20/21/22 |
| Safety Statements | 16-36 |
| RIDADR | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| RTECS | NY2774200 |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | III |
| HS Code | 29349990 |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
