2,4-Dimethoxybenzylamine , 98% , 20781-20-8

CAS NO.：20781-20-8

Empirical Formula: C9H13NO2

Molecular Weight: 167.21

MDL number: MFCD00052811

EINECS: 672-586-1

PRODUCT Properties

• Boiling point: 95 °C0.2 mm Hg(lit.)
• Density: 1.113 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.549(lit.)
• Flash point: >230 °F
• storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• form: Liquid
• pka: 9.39±0.10(Predicted)
• color: Clear colorless to slightly yellow
• Sensitive: Air Sensitive
• InChI: InChI=1S/C9H13NO2/c1-11-8-4-3-7(6-10)9(5-8)12-2/h3-5H,6,10H2,1-2H3
• InChIKey: QOWBXWFYRXSBAS-UHFFFAOYSA-N
• SMILES: C1(CN)=CC=C(OC)C=C1OC
• CAS DataBase Reference: 20781-20-8(CAS DataBase Reference)

Description and Uses

2,4-Dimethoxybenzylamine is an amine nucleophile used to investigate the 1,4- reactivity of 5-bromo-2-indene-1-one. It may be used in the following studies:

• As an ammonia equivalent in the concise synthesis of a series of 2,4,5-trisubstituted oxazoles, via a tandem Ugi/Robinson-Gabriel reaction sequence.
• Total synthesis of (-)-muraymycin (MRY) D₂ and its epimer, the antibacterial nucleoside natural product.
• Two-step synthesis of amide derivatives of uracil polyoxin C (UPOC) methyl ester using the Ugi reaction.
• Synthesis of N-hydroxythiourea.
• Synthesis of anti-HIV-1 agents.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H314
• Precautionary statements: P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
• Hazard Codes: C
• Risk Statements: 34
• Safety Statements: 26-27-36/37/39-45
• RIDADR: UN 2735 8/PG 3
• WGK Germany: 3
• RTECS: DP4430000
• HazardClass: 8
• PackingGroup: III
• HS Code: 29222990
• Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)