dehydroepiandrosterone sulfate sodium salt , >99% , 1099-87-2

Synonym(s):
Dehydroepiandrosterone 3-sulfate sodium salt

CAS NO.：1099-87-2

Empirical Formula: C19H27NaO5S

Molecular Weight: 390.47

MDL number: MFCD00010470

EINECS: 214-152-2

PRODUCT Properties

• Melting point: 148-149 °C (dec.)(lit.)
• refractive index: 10 ° (C=4, MeOH)
• Flash point: 9℃
• storage temp.: -20°C
• solubility: methanol: clear to hazy
• form: powder
• color: white to off-white
• Merck: 14,2871
• InChIKey: GFJWACFSUSFUOG-QGVZUKINNA-M
• SMILES: [C@]12([H])CC[C@]3(C)C(CC[C@@]3([H])[C@]1([H])CC=C1C[C@@H](OS([O-])(=O)=O)CC[C@]21C)=O.[Na+] |&1:0,4,9,11,17,25,r|
• CAS DataBase Reference: 1099-87-2(CAS DataBase Reference)

Description and Uses

Dehydroepiandrosterone sulfate (DHEAS) is a metabolite of dehydroepiandrosterone that is the major secretory product of adrenal glands and is the predominant circulating precursor for active steroid hormones in humans. For example, in the fetoplacental-maternal unit, DHEAS acts as the primary precursor for placental estrogen biosynthesis. A normal circulating concentration of DHEAS is ~10 μM in young adults and is dramatically increased in some adrenocortical disorders.

An active agent in the preparation of a pharmaceutical for the treatment of asthma or other respiratory diseases.

Safety

• Symbol(GHS): GHS02,GHS06,GHS08
• Signal word: Danger
• Hazard statements: H225-H301+H311+H331-H370
• Precautionary statements: P210-P260-P280-P301+P310-P311
• Hazard Codes: F,C,T
• Risk Statements: 11-34-39/23/24/25-23/24/25
• Safety Statements: 16-26-36/37/39-45-36/37-7
• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 3
• RTECS: BV8397400
• Toxicity: dog,LD50,intravaginal,> 500mg/kg (500mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 444, 1998.