1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (ammonium salt) , >99% , 474922-20-8

Synonym(s):
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (sodium salt)

CAS NO.：474922-20-8

Empirical Formula:

Molecular Weight:

MDL number:

PRODUCT Properties

• solubility: Ethanol: Sparingly soluble: 1-10 mg/ml
• InChIKey: MFOLYTNLQCGGBD-UHFFFAOYSA-N
• SMILES: C(COC(=O)CCCCCCCCCCCCCCCCC)(OC(=O)CCCCCCCCCCCCCCCCC)COP(O)(=O)OCCNC(=O)O{-}CC{+n}OCC(=O)O.N

Description and Uses

DSPE-PEG-CH2COOH, MW 2,000 is a PEG polymer with DSPE and carboxylic acid end groups. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The -COOH group can react with primary amines in the presence of activator, such as EDC or HATU, to form a stable amide bond.

DSPE-PEG-Carboxylic Acid is a phospholipid PEG conjugate. DSPE-PEG-Carboxylic Acid can be widely used in the delivery of targeted agents and genes[1].