Home Categories 2',7'-Difluorofluorescein
A3357512

2',7'-Difluorofluorescein , ≥95%(HPLC) , 195136-58-4

CAS NO.:195136-58-4

Empirical Formula: C20H10F2O5

Molecular Weight: 368.29

MDL number: MFCD01311849

Pack Size Price Stock Quantity
100MG RMB1550.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 591.7±50.0 °C(Predicted)
Density  1.70±0.1 g/cm3(Predicted)
solubility  Insoluble in water; soluble in N,Ndimethylformamide
form  A solid
pka 4.8, (at 22℃);4.7, (at 22℃)
color  Orange powder
Appearance Solid Powder
λmax 490 nm (Buffer pH 9.0)
Major Application As geothermal tracers;TiO2 nanoparticles for light energy conversion
Biological Applications Detecting atherosclerosis;detecting/monitoring amyloid Aβ production/accumulation/aggregation/disaggregation; diagnosing Alzheimer’s disease;estimating/measuring concentration of cortisol, melatonin, secretory IgA in body fluids;11 evaluating cetuximab-based imaging probe to target epidermal growth factor receptor (EGFR);examining biodistribution of proteins;investigating/measuring protein-protein and protein-nucleic acid interactions;measuring pH of apoplast at the root surface;visualizing hair follicles;as a substrate for measuring β-lactamase activity,phosphatases activity
InChI InChI=1S/C20H10F2O5/c21-13-5-11-17(7-15(13)23)26-18-8-16(24)14(22)6-12(18)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,23-24H
InChIKey FJXJIUHGLVUXQP-UHFFFAOYSA-N
SMILES C12(C3=C(C=C(O)C(F)=C3)OC3=C1C=C(F)C(O)=C3)C1=C(C=CC=C1)C(=O)O2

Description and Uses

2',7'-difluorofluorescein is used to create bioconjugates with peptides, proteins (especially antibodies), nucleotides, oligonucleotides, drugs, hormones, lipids, and other biomolecules.

2'',7''-Difluorofluorescein is a reactant used in the synthesis of biarsenical probes that inhibit protein tyrosine phosphatases.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338