A3494712
1-(3,4-Dimethylphenyl)-3-methyl-5-pyrazolone , ≥97.0% , 277299-70-4
CAS NO.：277299-70-4
Empirical Formula: C12H14N2O
Molecular Weight: 202.25
MDL number: MFCD09795980
EINECS: 1592732-453-0
| Pack Size | Price | Stock | Quantity |
| 1G | RMB72.80 | In Stock |
|
| 5G | RMB347.20 | In Stock |
|
| 25g | RMB1220.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 121.0 to 125.0 °C |
| Boiling point: | 338.5±52.0 °C(Predicted) |
| Density | 1.121 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 0.79±0.40(Predicted) |
| color | Pale Beige to Light Beige |
| InChI | InChI=1S/C12H14N2O/c1-8-4-5-11(6-9(8)2)14-12(15)7-10(3)13-14/h4-7,13H,1-3H3 |
| InChIKey | HBWBJCSXUJIDGN-UHFFFAOYSA-N |
| SMILES | N1C(C)=CC(=O)N1C1=CC=C(C)C(C)=C1 |
Description and Uses
2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one, is an impurity of Eltrombopag (E508000), which is agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H335-H319-H315 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501 |
| HS Code | 2933.19.9000 |
