A3950212
Ethyl chloroacetate , AR,99% , 105-39-5
Synonym(s):
Chloroacetic acid ethyl ester;Ethyl chloroacetate
CAS NO.：105-39-5
Empirical Formula: C4H7ClO2
Molecular Weight: 122.55
MDL number: MFCD00000932
EINECS: 203-294-0
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | -26 °C (lit.) |
| Boiling point: | 143 °C (lit.) |
| Density | 1.145 g/mL at 25 °C (lit.) |
| vapor density | 4.23 (vs air) |
| vapor pressure | 10 mm Hg ( 38 °C) |
| refractive index | n |
| Flash point: | 150 °F |
| storage temp. | Store below +30°C. |
| solubility | 12.3g/l |
| form | Liquid |
| color | Clear colorless |
| Odor | Extremely irritating; fruity; pungent |
| explosive limit | 2.6%(V) |
| Water Solubility | 20 g/L (20 ºC) |
| Merck | 14,3783 |
| BRN | 506455 |
| Henry's Law Constant | 2.6×10-1 mol/(m3Pa) at 25℃, Brockbank (2013) |
| Dielectric constant | 11.6（20℃） |
| Stability: | Stable. Incompatible with acids, bases, oxidizing agents, reducing agents. Flammable. |
| InChI | 1S/C4H7ClO2/c1-2-7-4(6)3-5/h2-3H2,1H3 |
| InChIKey | VEUUMBGHMNQHGO-UHFFFAOYSA-N |
| SMILES | CCOC(=O)CCl |
| LogP | 0.940 |
| CAS DataBase Reference | 105-39-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethyl chloroacetate(105-39-5) |
| EPA Substance Registry System | Ethyl chloroacetate (105-39-5) |
Description and Uses
Ethyl chloroacetate is a water-white liquidwith a pungent, fruity odor. Molecular weight = 122.56;Boiling point = 145℃. Freezing point = - 27℃; Flashpoint = 64℃. Hazard Identification (based on NFPA-704 MRating System): Health: 3, Flammability 3, Reactivity 0.Insoluble in water.
Ethyl chloroacetate is a reagent used in the preparation of 5 member heterocycles. It is used as pharmaceutical and organic intermediate. It is used as a solvent for organic synthesis and the production of pesticides (such as sodium fluoroacetate).
Safety
| Symbol(GHS) |      GHS02,GHS05,GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H301+H311+H331-H315-H318-H371-H317-H400-H226 |
| Precautionary statements | P501-P273-P272-P270-P240-P260-P210-P233-P243-P241-P242-P271-P264-P280-P370+P378-P391-P308+P311-P361+P364-P303+P361+P353-P333+P313-P301+P310+P330-P304+P340+P311-P305+P351+P338+P310-P403+P233-P403+P235-P405 |
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | T,N |
| Risk Statements | 23/24/25-50-10 |
| Safety Statements | 45-61-7/9-16 |
| RIDADR | UN 1181 |
| WGK Germany | 2 |
| RTECS | AF9110000 |
| Autoignition Temperature | 452 °C |
| TSCA | TSCA listed |
| HS Code | 2915 40 00 |
| HazardClass | 6.1 |
| PackingGroup | II |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Acute Tox. 1 Inhalation Acute Tox. 2 Dermal Acute Tox. 3 Oral Aquatic Acute 1 Eye Dam. 1 Flam. Liq. 3 Skin Irrit. 2 |
| Hazardous Substances Data | 105-39-5(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 180 mg/kg LD50 dermal Rat 161 mg/kg |
| REACH Registrations | Active |
| Limited Quantities | 100ml (liquid) or 0.5 Kg (solid) |
| Excepted Quantities | Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml) |
