A3962612
4-Ethoxyaniline , 98% , 156-43-4
Synonym(s):
p-Phenetidine;4-Ethoxyaniline
CAS NO.：156-43-4
Empirical Formula: C8H11NO
Molecular Weight: 137.18
MDL number: MFCD00007865
EINECS: 205-855-5
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 2-5 °C(lit.) |
| Boiling point: | 250 °C(lit.) |
| Density | 1.065 g/mL at 25 °C(lit.) |
| vapor pressure | 2.93Pa at 25℃ |
| refractive index | n |
| Flash point: | 240 °F |
| storage temp. | 2-8°C |
| solubility | 20g/l |
| pka | 5.2(at 28℃) |
| form | A liquid |
| color | Clear Yellow |
| PH | 8 (1g/l, H2O, 20℃) |
| Water Solubility | practically insoluble |
| Sensitive | Air Sensitive |
| Merck | 14,7228 |
| BRN | 606666 |
| Dielectric constant | 7.3（21℃） |
| Stability: | Stable, but light and air sensitive. Combustible. Incompatible with strong oxidizing agents. |
| InChIKey | IMPPGHMHELILKG-UHFFFAOYSA-N |
| CAS DataBase Reference | 156-43-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Ethoxyaniline(156-43-4) |
| EPA Substance Registry System | p-Phenetidine (156-43-4) |
Description and Uses
A toxic metabolite of Phenacetin (P294580) which exhibits high renal toxicity. p-Phenetidine also reduced COX-1 and COX-2 expression in neutrophils.
Safety
| Symbol(GHS) |   GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H317-H319-H341 |
| Precautionary statements | P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338-P308+P313 |
| Hazard Codes | T,Xi,Xn |
| Risk Statements | 23/24/25-33-68-43-36-20/21/22 |
| Safety Statements | 28-36/37-45-46 |
| RIDADR | UN 2311 6.1/PG 3 |
| WGK Germany | 1 |
| RTECS | SI6465500 |
| F | 8-10 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29222200 |
| Toxicity | LD50 orl-rat: 580 mg/kg GISAAA 35(8),28,70 |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
