Epothilone A , ≥98% , 152044-53-6

Synonym(s):
EpoA

CAS NO.：152044-53-6

Empirical Formula: C26H39NO6S

Molecular Weight: 493.66

MDL number: MFCD26960884

Pack Size	Price	Stock	Quantity
1MG	RMB479.20	In Stock
5MG	RMB892.00	In Stock
others			Enquire

Update time: 2022-07-08

PRODUCT Properties

Melting point:	95℃
alpha	D21 -47.1° (c = 1.0 in methanol)
Boiling point:	683.3±55.0 °C(Predicted)
Density	1.143
storage temp.	-20°C
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
pka	13.57±0.70(Predicted)
form	solid
color	White to Off-White
Stability:	Stable under recommended storage conditions., Stable Under Recommended Storage C
InChIKey	HESCAJZNRMSMJG-KKQRBIROSA-N
SMILES	[C@]12([H])[C@]([H])(O1)CCC[C@H](C)[C@H](O)[C@@H](C)C(=O)C(C)(C)[C@@H](O)CC(=O)O[C@H](/C(/C)=C/C1=CSC(C)=N1)C2

Description and Uses

The epothilones are a novel class of antineoplastic agents possessing antitubulin activity. Epothilone A, B isolated from Sorangium cellulosum was associated with cell cycle arrest at G2/M transition and apoptosis that was resisted with overexpression of β-tubulin and P-glycoprotein in human bladder carcinoma cell.