Forskolin , ≥98% , 66575-29-9

Synonym(s):
7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one;7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxy-labd-14-en-11-one, Colforsin;Coleonol;Colforsin;Forskolin, Coleus forskohlii - CAS 66575-29-9 - Calbiochem

CAS NO.：66575-29-9

Empirical Formula: C22H34O7

Molecular Weight: 410.5

MDL number: MFCD00082317

EINECS: 266-410-9

PRODUCT Properties

• Melting point: 282-232 °C
• Boiling point: 520℃
• alpha: D25 -26.19° (c = 1.68 in CHCl3)
• Density: 1.23
• refractive index: 1.5300 (estimate)
• Flash point: 172℃
• storage temp.: room temp
• solubility: DMSO: 5 mg/mL stable at least 6 months at room temperature
• form: powder
• pka: 11.00±0.70(Predicted)
• color: off-white
• biological source: Coleus forskohlii
• Water Solubility: Soluble in ethanol, dimethylsulfoxide and chloroform. Insolule in water.
• λmax: 305nm(lit.)
• Merck: 14,2476
• BRN: 1692716
• Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
• Major Application: food and beverages
• InChIKey: OHCQJHSOBUTRHG-KGGHGJDLSA-N
• SMILES: CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C
• LogP: 2.406 (est)
• CAS DataBase Reference: 66575-29-9

Description and Uses

Forskolin (66575-29-9) is a widely used adenylate cyclase activator.1 Forskolin also is a positive inotropic agent, vasodilator and induces platelet activation among other activities.2-5

adenylate cyclase activator, antiglaucoma, hypotensive, vasodilator

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H312
• Precautionary statements: P280-P302+P352+P312-P362+P364-P501
• Hazard Codes: Xn
• Risk Statements: 21
• Safety Statements: 22-36/37
• WGK Germany: 3
• RTECS: QL6150000
• F: 10-21
• HS Code: 29329990
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Dermal