Formononetin , 98% , 485-72-3
Synonym(s):
Formonetin;Formononetol;7-Hydroxy-3-(4?-methoxyphenyl)-4H-benzopyran-4-one;7-Hydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one;7-Hydroxy-3-(4-methoxyphenyl)chromone
CAS NO.：485-72-3
Empirical Formula: C16H12O4
Molecular Weight: 268.26
MDL number: MFCD00016948
EINECS: 207-623-9
| Pack Size | Price | Stock | Quantity |
| 1G | RMB31.20 | In Stock |
|
| 5G | RMB68.80 | In Stock |
|
| 25g | RMB155.20 | In Stock |
|
| 100g | RMB694.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 256-260 °C |
| Boiling point: | 331.43°C (rough estimate) |
| Density | 1.1529 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.4350 (estimate) |
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO (up to 100 mg/ml). |
| form | Powder |
| pka | 6.99±0.20(Predicted) |
| color | White to light beige |
| λmax | 300nm(EtOH)(lit.) |
| Merck | 14,4244 |
| BRN | 237979 |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
| InChIKey | HKQYGTCOTHHOMP-UHFFFAOYSA-N |
| LogP | 1.7 at 25℃ |
| CAS DataBase Reference | 485-72-3(CAS DataBase Reference) |
| EPA Substance Registry System | 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-methoxyphenyl)- (485-72-3) |
Description and Uses
Formononetin (485-72-3) is a naturally occurring isoflavone isolated from Astragalus and other plants. Increases adipocyte thermogenesis by modulating PPARγ activity.1?Activates AMP-activated protein kinase/β-catenin signaling to inhibit adipogenesis.2?Accelerates wound repair by increasing expression of Egr-1 transcription factor.3?Potential cancer chemopreventive and chemotherapeutic.4?Provides neuroprotection against traumatic brain injury by inhibition of neuroinflammation in a rat model.5
Formononetin is an isoflavone found as one of the main plant estrogens in animal feed. When metabolized in the rumen this compound transforms into a potent estrogen.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 37/39-26-36 |
| WGK Germany | 3 |
| RTECS | DJ3100114 |
| HS Code | 29329990 |
