Guandine thiocyanate , ≥99% , 593-84-0

Synonym(s):
Guanidine thiocyanate;Guanidine isothiocyanate;GTC;Guanidinium thiocyanate;Guanidinium isothiocyanate

CAS NO.：593-84-0

Empirical Formula: CH5N3.CHNS

Molecular Weight: 118.16

MDL number: MFCD00013027

EINECS: 209-812-1

PRODUCT Properties

• Melting point: 120-122 °C(lit.)
• Density: 1.103 g/mL at 20 °C
• bulk density: 630kg/m3
• vapor pressure: 0Pa at 20℃
• refractive index: n20/D 1.482
• storage temp.: 20-25°C
• solubility: H₂O: 6 M at 20 °C, clear, colorless
• pka: 12.5[at 20 ℃]
• form: Crystals or Crystalline Powder
• Specific Gravity: 1.152
• color: White or colorless
• Odor: Odorless
• PH Range: 4.8 - 6.0
• PH: 4.8-6.0 (1420g/l, H2O, 20℃)(saturated solution)
• biological source: synthetic (organic)
• Water Solubility: Soluble in water and ethanol
• Sensitive: Light Sensitive
• BRN: 3563461
• Stability: Stability Stable, but light sensitive. Incompatible with acids (contact releases very toxic gas), strong oxidising agents.
• InChIKey: ZJYYHGLJYGJLLN-UHFFFAOYSA-N
• LogP: -1.5--1.42 at 20℃
• CAS DataBase Reference: 593-84-0(CAS DataBase Reference)
• EPA Substance Registry System: Thiocyanic acid, compd. with guanidine (1:1) (593-84-0)
• Absorption: cut-off at 280nm in H2O at 6M

Description and Uses

Guanidine thiocyanate has been used as a component of the stabilization buffer for RNA lysis. It can be used for deactivation of endogenous RNases leading to denaturation of nucleoprotein complexes. It is also suitable for denaturation of macromolecules such as nucleic acids and proteins and for RNA isolation.

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H302+H312+H332-H314-H412
• Precautionary statements: P260-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
• Hazard Codes: Xn,T,C
• Risk Statements: 20/21/22-32-52/53-36/37/38-34
• Safety Statements: 36/37-61-13-36-26-45-36/37/39
• RIDADR: 1759
• WGK Germany: 2
• RTECS: XL1225000
• F: 3-10
• TSCA: Yes
• HazardClass: 8
• PackingGroup: III
• HS Code: 29252000