Glutathione reduced ethyl ester , 90% , 92614-59-0

CAS NO.：92614-59-0

Empirical Formula: C12H21N3O6S

Molecular Weight: 335.38

MDL number: MFCD00156117

PRODUCT Properties

• Boiling point: 644.3±55.0 °C(Predicted)
• Density: 1.314±0.06 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: PBS (pH 7.2): 10 mg/ml; Water: 20 mg/ml
• form: A crystalline solid
• pka: 2.21±0.10(Predicted)
• color: White to off-white
• InChI: 1S/C12H21N3O6S/c1-2-21-10(17)5-14-11(18)8(6-22)15-9(16)4-3-7(13)12(19)20/h7-8,22H,2-6,13H2,1H3,(H,14,18)(H,15,16)(H,19,20)/t7-,8-/m0/s1
• InChIKey: JKRODHBGNBKZLE-YUMQZZPRSA-N
• SMILES: CCOC(=O)CNC(=O)[C@H](CS)NC(=O)CC[C@H](N)C(O)=O

Description and Uses

Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. GSH ethyl ester is a cell-permeable derivative of GSH that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH ethyl ester has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals.

Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. GSH ethyl ester is a cell permeable derivative of GSH that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH ethyl ester has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals.

Safety

• PPE: Eyeshields, Gloves, type N95 (US)
• WGK Germany: 3
• Storage Class: 11 - Combustible Solids