1H-Imidazole-4-carboxylic acid , 98% , 1072-84-0

CAS NO.：1072-84-0

Empirical Formula: C4H4N2O2

Molecular Weight: 112.09

MDL number: MFCD00082203

EINECS: 214-017-8

PRODUCT Properties

• Melting point: 294-295 °C (lit.)
• Boiling point: 495.0±18.0 °C(Predicted)
• Density: 1.524±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: Aqueous Acid (sparingly)
• pka: 2.69±0.10(Predicted)
• form: Liquid
• color: Clear colorless
• InChI: InChI=1S/C4H4N2O2/c7-4(8)3-1-5-2-6-3/h1-2H,(H,5,6)(H,7,8)
• InChIKey: NKWCGTOZTHZDHB-UHFFFAOYSA-N
• SMILES: C1NC(C(O)=O)=CN=1
• CAS DataBase Reference: 1072-84-0(CAS DataBase Reference)

Description and Uses

4-Imidazolecarboxylic acid (ICA) was used in the synthesis of triphenymethyl-protected 4-imidazole carboxylic acid (trityl-ImCOOH) which is employed to functionalize poly(propylene imine) dendrimers.
It may be used in the following studies:

• In the synthesis of lanthanide sulfate–carboxylates, [Ln(HIMC)(SO₄)(H₂O)] (Ln = Dy and Eu, HIMC = 4-imidazolecarboxylic acid) by in situ decarboxylation in the presence of Cu(II) ions.
• As an internal standard to obtain calibration curve by plotting the peak area ratios of histamine (HA) and several metabolites isolated from C3H/HeNCrj mice hair relative to ICA.
• In the synthesis of tetranuclear manganese carboxylate complexes possessing imidazole-based N/O chelating ligands.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• RTECS: NI4001000
• HazardClass: IRRITANT
• HS Code: 29332900