A5020312
Isoxazole-5-carboxylic acid , 98% , 21169-71-1
| Pack Size | Price | Stock | Quantity |
| 1G | RMB68.00 | In Stock |
|
| 5G | RMB249.60 | In Stock |
|
| 25G | RMB925.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 144-148 °C(lit.) |
| Boiling point: | 211.74°C (rough estimate) |
| Density | 1.5808 (rough estimate) |
| refractive index | 1.4543 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Powder |
| pka | 2.29±0.10(Predicted) |
| color | Slightly yellow |
| Water Solubility | Slightly soluble in water. |
| Sensitive | Moisture Sensitive |
| InChI | InChI=1S/C4H3NO3/c6-4(7)3-1-2-5-8-3/h1-2H,(H,6,7) |
| InChIKey | MIIQJAUWHSUTIT-UHFFFAOYSA-N |
| SMILES | O1C(C(O)=O)=CC=N1 |
| CAS DataBase Reference | 21169-71-1(CAS DataBase Reference) |
Description and Uses
Reaction conditions were found to allow the exclusive formation of isoxazole-5-carboxylic acid derivatives by conjugate addition, in acidic medium, of hydroxylamine to β-alkoxyvinyl trichloromethyl ketone in synthesis and reactivity of isoxazoles. Isoxazole-5-carboxylic acid participates in the Synthesis and evaluation of acylguanidine FXa inhibitors. 1, 1, 1-trichloro-4-methoxy-3-penten-2-one postulated in the preparation of isoxazole-5-carboxylic acid from trichloroacetyl chloride, ethyl vinyl ether and hydroxylamine is developed in a fully saturated nitrogen atom theerefore there is no possibility of conjugation with 4- substituents.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 24/25-25-24-36-26 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 29349990 |
