Leu-Leu-Leu , 98% , 10329-75-6

CAS NO.：10329-75-6

Empirical Formula: C18H35N3O4

Molecular Weight: 357.49

MDL number: MFCD00038309

PRODUCT Properties

• Boiling point: 589.6±45.0 °C(Predicted)
• Density: 1.057
• storage temp.: −20°C
• pka: 3.39±0.10(Predicted)
• form: powder
• color: white
• optical activity: -39.47°(C=0.46g/100mL, NAOH, 20°C, 589nm)
• InChI: InChI=1S/C18H35N3O4/c1-10(2)7-13(19)16(22)20-14(8-11(3)4)17(23)21-15(18(24)25)9-12(5)6/h10-15H,7-9,19H2,1-6H3,(H,20,22)(H,21,23)(H,24,25)/t13-,14-,15-/m0/s1
• InChIKey: DNDWZFHLZVYOGF-KKUMJFAQSA-N
• SMILES: C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)N

Description and Uses

The tripeptide trileucine (Leu-Leu-Leu) is found in casein and soy protein. This substance could increase the endothelial release of TXB₂ which is a stable marker of TXA₂. Inhibitor of human liver alanine aminopeptidase, Ki 0.054 mM. The addition of trileucine improved the aerosol performance and stability of spray-dried powders for inhalation.

Leu-Leu-Leu could be used to synthesize Cl^-.H₂⁺-Leu-Leu-Leu-OMe (a hydrochloric acid salt of Peptide derivative IIa).

Safety

• WGK Germany: 3