Leonurine , ≥98%(HPLC) , 24697-74-3

Synonym(s):
4-Guanidino-1-butanol syringate;4-Guanidinobutyl 4-hydroxy-3,5-dimethoxybenzoate;SCM-198

CAS NO.：24697-74-3

Empirical Formula: C14H21N3O5

Molecular Weight: 311.33

MDL number: MFCD09839432

EINECS: 683-174-6

PRODUCT Properties

• Melting point: 238 °C
• Boiling point: 496.7±55.0 °C(Predicted)
• Density: 1.29±0.1 g/cm3(Predicted)
• storage temp.: Keep in dark place,Inert atmosphere,2-8°C
• solubility: DMSO: soluble2mg/mL, clear (warmed)
• pka: 8.26±0.25(Predicted)
• form: powder
• color: white to beige
• Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
• InChI: InChI=1S/C14H21N3O5/c1-20-10-7-9(8-11(21-2)12(10)18)13(19)22-6-4-3-5-17-14(15)16/h7-8,18H,3-6H2,1-2H3,(H4,15,16,17)
• InChIKey: WNGSUWLDMZFYNZ-UHFFFAOYSA-N
• SMILES: C(OCCCCNC(N)=N)(=O)C1=CC(OC)=C(O)C(OC)=C1

Description and Uses

An amorphous alkaloid, leonurine has been obtained from the leaves of Leonurus sibiricus L. and is characterized as the crystalline hydrochloride hydra te, m.p. 19l-4°C. Hydrolysis yields syringic acid and Q-hydroxybutylguanidine. The total synthesis of the alkaloid has been achieved, confirming the above structure.

Leonurine is a pseudoalkaloid that has been isolated from Leonotis leonurus. A natural product with antioxidant, anti-inflammatory and cardioprotective properties for the treatment of wild variety of conditions including stroke, cerebral thrombosis and cardiovascular diseases.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-24/25
• WGK Germany: 3
• HS Code: 29399990