Methyl 4-hydroxybenzoate sodium salt , PhEur , 5026-62-0

Synonym(s):
4-Hydroxybenzoic acid methyl ester sodium salt, Methylparaben sodium salt;Methyl 4-hydroxybenzoate sodium salt;Methylis parahydroxybenzoas natricum;Sodium methyl 4-hydroxybenzoate

CAS NO.：5026-62-0

Empirical Formula: C8H7NaO3

Molecular Weight: 174.13

MDL number: MFCD00016470

EINECS: 225-714-1

PRODUCT Properties

• Melting point: >125°C
• Density: 1.42 g/cm3 (20 °C)
• storage temp.: Store at +15°C to +25°C.
• solubility: Freely soluble in water, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
• pka: 8.4[at 20 ℃]
• form: Powder
• color: White
• PH: 9.7-10.3 (1g/l, H2O)
• Water Solubility: 418g/L at 20℃
• BRN: 4165000
• InChI: InChI=1S/C8H8O3.Na.H/c1-11-8(10)6-2-4-7(9)5-3-6;;/h2-5,9H,1H3
• InChIKey: PESXGULMKCKJCC-UHFFFAOYSA-M
• SMILES: C(C1C=CC(O)=CC=1)(=O)OC.[NaH]
• LogP: -0.63 at 20℃
• CAS DataBase Reference: 5026-62-0(CAS DataBase Reference)
• EPA Substance Registry System: Methylparaben sodium (5026-62-0)

Description and Uses

Methyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like propyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard methyl 4-hydroxybenzoate.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H315-H318-H412
• Precautionary statements: P273-P280-P302+P352-P305+P351+P338+P310
• Hazard Codes: Xn
• Risk Statements: 22
• Safety Statements: 22-24/25
• WGK Germany: 1
• RTECS: DH2455000
• Autoignition Temperature: >600 °C
• HS Code: 29182930
• Toxicity: LD50 orally in Rabbit: > 5000 mg/kg