A5394712
4-Methylumbelliferone , 98% , 90-33-5
Synonym(s):
β-Methylumbelliferone;4-Methylumbelliferone;4-MU;7-Hydroxy-4-methylcoumarin
CAS NO.：90-33-5
Empirical Formula: C10H8O3
Molecular Weight: 176.17
MDL number: MFCD00006866
EINECS: 201-986-7
| Pack Size | Price | Stock | Quantity |
| 5g | RMB28.80 | In Stock |
|
| 25G | RMB39.20 | In Stock |
|
| 100G | RMB103.20 | In Stock |
|
| 500G | RMB453.60 | In Stock |
|
| 2.5kg | RMB1919.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 188.5-190 °C(lit.) |
| Boiling point: | 267.77°C (rough estimate) |
| Density | 1.1958 (rough estimate) |
| refractive index | 1.5036 (estimate) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water; slightly soluble in ethanol, ether,chloroform; soluble inmethanol |
| form | Crystalline Powder |
| pka | 7.79(at 25℃) |
| color | off-white to yellow |
| PH Range | Green 1 uorescent (0.0) to weak blue 1 uorescent (2.0);Weak blue 1 uorescent (6.5) blue 1 uorescent (8.0) |
| Water Solubility | slightly soluble |
| λmax | 221nm, 251nm, 322nm |
| Merck | 14,4854 |
| BRN | 142217 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. |
| Major Application | color filter, electroluminescent displays, document security processes, lasers, integrated circuits, liquid crystal displays, surface brightening composition, oil products, teeth whitening agent, lysosomal enzyme assay, substrate for lipase, determining protein-protein-interactions in living cells, Antitrypanosomal, antileishmanial, anticancer, antiHIV, antimalarial, antibacterial, antifungal |
| InChIKey | HSHNITRMYYLLCV-UHFFFAOYSA-N |
| LogP | 2.370 (est) |
| CAS DataBase Reference | 90-33-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Coumarin, 7-hydroxy-4-methyl-(90-33-5) |
| EPA Substance Registry System | 4-Methylumbelliferone (90-33-5) |
Description and Uses
4-methylumbelliferone (4-MU) is a dietary supplement that inhibits hyaluronic acid (HA) synthesis. HA is a prominent component of the extracellular matrix at many sites of chronic inflammation, including type 1 diabetes (T1D), multiple sclerosis, and numerous malignancies. 4-MU is an already approved drug in Europe and Asia called “hymecromone” where it is used to treat biliary spasm.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H303-H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-20/21/22 |
| Safety Statements | 26-37/39-36 |
| WGK Germany | 2 |
| RTECS | GN7000000 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29329990 |
| Toxicity | LD50 oral in rat: 3850mg/kg |
