A5400712
Methyl isothiocyanate , 98% , 556-61-6
Synonym(s):
High affinity nerve growth factor receptor;MTC;NTRK1;TRK;TRKA
CAS NO.：556-61-6
Empirical Formula: C2H3NS
Molecular Weight: 73.12
MDL number: MFCD00004818
EINECS: 209-132-5
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 30-34 °C(lit.) |
| Boiling point: | 117-118 °C(lit.) |
| Density | 1.069 g/mL at 25 °C(lit.) |
| vapor pressure | 21 mm Hg ( 20 °C) |
| refractive index | nD37 1.5258 |
| FEMA | 4426 | METHYL ISOTHIOCYANATE |
| Flash point: | 90 °F |
| storage temp. | 2-8°C |
| solubility | H2O: slightly soluble |
| form | Low Melting Solid |
| color | White to pale yellow |
| Odor | at 0.01 % in propylene glycol. pungent mustard horseradish |
| Odor Type | pungent |
| biological source | rabbit |
| Water Solubility | 7.6 g/L |
| Sensitive | Moisture Sensitive |
| Merck | 14,6092 |
| JECFA Number | 1884 |
| BRN | 605319 |
| Specific Activity | 19-25nmol/min·mg |
| Henry's Law Constant | 1.7×10-1 mol/(m3Pa) at 25℃, Burkholder et al. (2019) |
| Stability: | Stable. Incompatible with strong oxidizing agents, alcohols, strong bases, amines. |
| InChIKey | LGDSHSYDSCRFAB-UHFFFAOYSA-N |
| LogP | 1.3 at 20℃ |
| CAS DataBase Reference | 556-61-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Methane, isothiocyanato-(556-61-6) |
| EPA Substance Registry System | Methyl isothiocyanate (556-61-6) |
Description and Uses
Methyl iso thio cyanate is the organo sulfur compound with the formula CH3N = C = S . This low melting colorless solid is a powerful lachrymator. As a precursor to a variety of valuable bioactive compounds, it is the most important organic iso thio cyanate in industry.
Pesticide and soil fumigant used to control insects, soil fungi, nematodes.
Safety
| Symbol(GHS) |      GHS02,GHS05,GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H310+H330-H301-H314-H371-H373-H317-H335-H410-H226 |
| Precautionary statements | P501-P273-P272-P260-P270-P262-P240-P210-P233-P243-P241-P242-P271-P264-P280-P284-P370+P378-P391-P308+P311-P361+P364-P303+P361+P353-P333+P313-P301+P330+P331-P301+P310+P330-P304+P340+P310-P305+P351+P338+P310-P403+P233-P403+P235-P405 |
| Hazard Codes | T,N |
| Risk Statements | 23/25-34-43-50/53 |
| Safety Statements | 36/37-38-45-60-61 |
| RIDADR | UN 2477 |
| WGK Germany | 3 |
| RTECS | PA9625000 |
| F | 21 |
| TSCA | TSCA listed |
| HazardClass | 6.1 |
| PackingGroup | I |
| HS Code | 29309090 |
| Storage Class | 10 - Combustible liquids |
| Hazardous Substances Data | 556-61-6(Hazardous Substances Data) |
| Toxicity | LD50 in rats, mice (mg/kg): 220, 110 orally; in rabbits (mg/kg): 33 dermally (Vernot); LD50 s.c. in mice: 0.05 g/kg (Klesse, Lukoschek) |
| REACH Registrations | Active |
| Excepted Quantities | Forbidden |
