4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside , 98% , 37067-30-4

Synonym(s):
4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside;4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-gluco-pyrano-side;4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside;4-Methylumbelliferyl-N-acetyl-β-D-glucosaminide - CAS 37067-30-4 - Calbiochem

CAS NO.：37067-30-4

Empirical Formula: C18H21NO8

Molecular Weight: 379.37

MDL number: MFCD00065481

EINECS: 253-333-0

PRODUCT Properties

• Melting point: 208-210 °C
• Boiling point: 507.24°C (rough estimate)
• Density: 1.4163 (rough estimate)
• refractive index: 1.5740 (estimate)
• storage temp.: -20°C
• solubility: DMF: 20 mg/mL, clear, colorless
• pka: 12.87±0.70(Predicted)
• form: Crystalline solid
• color: White to Off-White
• λmax: 360nm(Phosphate buffer sol.)(lit.)
• BRN: 1693397
• Stability: Light Sensitive - Protect from Light
• LogP: 0.340 (est)
• CAS DataBase Reference: 37067-30-4(CAS DataBase Reference)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 7-[[2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl]oxy]-4-methyl- (37067-30-4)

Description and Uses

4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE is used for the assay of b-Acetylglucosaminidase. A fluorogenic substrate used for the diagnosis of GM2 gangliosidoses in leukocytes. Genetic defects in human b-hexosaminidase isozy mes (Hex A & Hex B) result in various clinical and biochemical types of GM2 gangliosidosis. They include Tay Sachs disease, Sandhoff disease and other forms. Fluorescence: max. Abs. l = 325nm, max. Em. l = 378nm

Safety

• Symbol(GHS): GHS05,GHS02
• Signal word: Danger
• Hazard statements: H314-H226
• Precautionary statements: P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P235-P405
• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10-21
• HS Code: 29321900