A5485112
(S)-(+)-1-Methyl-3-pyrrolidinol , 98% , 104641-59-0
Synonym(s):
(S)-(+)-3-Hydroxy-N-methylpyrrolidine
CAS NO.：104641-59-0
Empirical Formula: C5H11NO
Molecular Weight: 101.15
MDL number: MFCD03788748
EINECS: 677-547-2
| Pack Size | Price | Stock | Quantity |
| 250MG | RMB24.80 | In Stock |
|
| 1G | RMB82.40 | In Stock |
|
| 5G | RMB207.20 | In Stock |
|
| 25g | RMB836.00 | In Stock |
|
| 100g | RMB2623.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| alpha | 6 º (c=1%, chloroform) |
| Boiling point: | 181-182 °C(lit.) |
| Density | 0.993 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 192 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Liquid |
| pka | 14.95±0.20(Predicted) |
| color | Colorless to yellow to brown |
| optical activity | [α]20/D +6°, c = 1 in chloroform |
| Sensitive | Air Sensitive & Hygroscopic |
| BRN | 4349394 |
| InChI | 1S/C5H11NO/c1-6-3-2-5(7)4-6/h5,7H,2-4H2,1H3/t5-/m0/s1 |
| InChIKey | FLVFPAIGVBQGET-YFKPBYRVSA-N |
| SMILES | CN1CC[C@H](O)C1 |
| CAS DataBase Reference | 104641-59-0(CAS DataBase Reference) |
Description and Uses
(S)-1-Methyl-3-pyrrolidinol is a useful synthetic intermediate. It is used to prepare diaryl acylaminopyrimidines as adenosine A2A antagonists. It is also used to synthesize (alkoxyamino)(pyridinylamino)pyrazinecarbonitriles as selective checkpoint kinase 1 (CHK1) inhibitors with oral antitumor activities.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H227-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338-P210e-P280a-P403+P235-P501a |
| target organs | Respiratory system |
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NA 1993 / PGIII |
| WGK Germany | 3 |
| RTECS | TM9570000 |
| HS Code | 29339900 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
