6-Methoxyindole , >98.0%(GC) , 3189-13-7

Synonym(s):
NSC 92517

CAS NO.：3189-13-7

Empirical Formula: C9H9NO

Molecular Weight: 147.17

MDL number: MFCD00022780

EINECS: 221-689-6

PRODUCT Properties

• Melting point: 90-92 °C (lit.)
• Boiling point: 105°C 0,2mm
• Density: 1.169±0.06 g/cm3(Predicted)
• Flash point: 105°C/0.2mm
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Methanol (Slightly)
• pka: 17.22±0.30(Predicted)
• form: Shiny Crystals
• color: White
• Sensitive: Light Sensitive
• BRN: 116483
• InChI: InChI=1S/C9H9NO/c1-11-8-3-2-7-4-5-10-9(7)6-8/h2-6,10H,1H3
• InChIKey: QJRWYBIKLXNYLF-UHFFFAOYSA-N
• SMILES: N1C2=C(C=CC(OC)=C2)C=C1
• CAS DataBase Reference: 3189-13-7(CAS DataBase Reference)
• NIST Chemistry Reference: Indole, 6-methoxy-(3189-13-7)

Description and Uses

6-Methoxyindole was used to study the fluorescence of protonated excited-state forms of serotonin and other related compounds in acid. It was used in the preparation of:

• tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, potential anticancer immunomodulator
• indolylindazoles and indolylpyrazolopyridines, interleukin-2 inducible T cell kinase inhibitors
• diindolyloxyindoles, anticancer agents
• benzoylpiperazinyl-indolyl ethane dione derivatives, HIV-1 inhibitors
• 3-aroylindoles as anticancer agents
• indolyl and isoquinolinyl anthranilates, PPARδ partial agonists
• heteroaryl ketones, VEGFR-2 inhibitors

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazard Note: Irritant/Keep Cold
• HazardClass: IRRITANT, LIGHT SENSITIVE
• HS Code: 29339900